Table 3.
Obstetrical and neonatal outcomes in relation to the COVID-19 status
| Outcome | All 4 centers COVID-19 positive (N=218) | RWJUH COVID-19 positive (n=49) | RWJUH COVID-19 negative (n=413) | RWJUH COVID-19 positive vs negative:relative risk (95% confidence interval) |
|---|---|---|---|---|
| Site of recruitment | ||||
| RWJUH | 49 (22.5) | 49 (100.0) | 413 (100.0) | — |
| SBMC | 61 (28.0) | — | — | — |
| MMC | 70 (32.1) | — | — | — |
| CMMC | 38 (17.4) | — | — | — |
| Gestational age at delivery (wk)a | 38.9 (2.5) | 39.1 (2.8) | 38.5 (2.7) | — |
| Mode of delivery | ||||
| Spontaneous vaginal | 164 (75.6) | 38 (77.6) | 266 (64.4) | 1.00 (Ref) |
| Operative vaginal | 9 (4.2) | 0 (0) | 11 (2.7) | — |
| Vaginal birth after cesarean delivery | 3 (1.4) | 2 (4.1) | 8 (1.9) | 1.60 (0.45–5.72) |
| Primary cesarean delivery | 18 (8.3) | 7 (14.3) | 65 (15.7) | 0.78 (0.36–1.67) |
| Repeat cesarean delivery | 23 (10.6) | 2 (4.1) | 62 (15.0) | 0.25 (0.06–1.01) |
| Delivery complications | ||||
| Preterm delivery | 50 (2.3) | 2 (4.0) | 48 (11.4) | 0.35 (0.09–1.40) |
| Spontaneous preterm delivery | 9 (4.2) | 1 (2.0) | 32 (7.8) | 0.27 (0.04–1.90) |
| Chorioamnionitis | 7 (3.2) | 2 (4.1) | 8 (1.9) | 1.92 (0.54–6.84) |
| Abnormal biophysical profile | 4 (1.8) | 2 (4.1) | 8 (1.9) | 1.92 (0.54–6.84) |
| Persistent category 2 tracing | 16 (7.4) | 4 (8.2) | 38 (9.2) | 0.89 (0.34–2.35) |
| Development of symptoms during admission | 7 (3.2) | 2 (4.1) | 0 (0) | — |
| Maternal outcomes | ||||
| Venous thromboembolism | 0 (0) | 0 (0) | 1 (0.2) | — |
| Intensive care unit admission | 0 (0) | 0 (0) | 3 (0.7) | — |
| Supplemental oxygen | 3 (1.4) | 2 (4.1) | 2 (0.5) | 4.87 (1.76–13.47) |
| Mechanical ventilation | 0 (0) | 0 (0) | 3 (0.7) | — |
| Death | 0 (0) | 0 (0) | 1 (0.2) | — |
| Neonatal outcomes | ||||
| Birthweight (g)a | 3249 (568) | 3228 (566) | 3191 (624) | |
| Neonatal intensive care unit admission | 56 (25.8) | 41 (83.7) | 65 (15.7) | 17.21 (8.33–35.57) |
| Positive COVID-19 PCR test result | 1 (0.7) | 0 (0) | 0 (0) | — |
| Respiratory distress syndrome | 8 (3.7) | 2 (4.1) | 20 (4.8) | 0.85 (0.22–3.28) |
| Intraventricular hemorrhage | 1 (0.5) | 0 (0) | 1 (0.2) | — |
| Necrotizing enterocolitis | 1 (0.5) | 0 (0) | 0 (0) | — |
| Death | 1 (0.5) | 1 (2.0) | 4 (1.0) | 1.90 (0.32–11.22) |
Data presented as number (percentage), unless indicated otherwise.
CMMC, Clara Maass Medical Center; MMC, Monmouth Medical Center; PCR, polymerase chain reaction; RWJUH, Robert Wood Johnson University Hospital; SBMC, Saint Barnabas Medical Center.
a
Data are presented as mean (standard deviation).
Hill. Asymptomatic COVID-19 in pregnancy. Am J Obstet Gynecol MFM 2021.