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. 2021 Jun 25;54(8):e13086. doi: 10.1111/cpr.13086

TABLE 1.

Overview of components involved in stress granules in germ cells

Components Function References
DAZL Prevent male germ cells from undergoing apoptosis upon heat stress 99
TIAR‐1 Promote fertility and embryonic development 106, 114
EIF2α As a protective mechanism against heat stress in mouse male germ cells 119
BOULE As conserved germ cell‐specific translational regulators 118
NANOS2 Stabilized NANOS2 may be responsible for the reduction of the spermatogonial progenitor cell (SPC) pool 117
MUSASHI‐1 Critical for constructing a functional BTB structure and maintaining spermatogenesis; regulating Sertoli cell fate following heat‐induced injury 113
DZIP1 Important for the formation of stress granules during the stress response 120
MAGE‐B2 Increase stress tolerance by inhibiting SG formation 12