FIG. 5.

Bioprinted breast cancer cells on NG2 knockout tissues have decreased proliferation and motility during ex vivo culture. Prelabeled DiI 4T1 murine breast cancer cells were bioprinted on wild-type, WT (A–C), or neuron-glial antigen 2 knockout, NG2 KO (D–F) mesometrium tissues containing intact microvasculature with its native physiology. Proliferation (G) and motility (H) of bioprinted 4T1 murine breast cancer cells on wild-type (black circle symbol) and neuron-glial antigen 2 knockout (purple triangle symbol) mesometrium tissues were quantified during ex vivo culture. Data are shown as the mean ± SEM and * represents p < 0.05, n = 7. Scale bars = 500 μm.