Table 1.
Summary of clinical findings. All patients presented 2 to 5 days following their 2nd vaccine dose with troponin and CRP elevation, and the viral serologies that were tested were negative. ECG and TTE abnormalities may be compared as well.
| Case number | Age and sex | Vaccine maker | Days from 2nd vaccine dose to presentation | Peak troponin-I (pg/mL) | CRP (mg/L) | Viral serologiesa | ECG abnormalities | TTE findings |
|---|---|---|---|---|---|---|---|---|
| 1 | 23F | Moderna | 5 | 16,263 | 41 | Negative | Down-sloping PR depressions, diffuse ST elevations | LVEF 55–60%, basal inferior and basal inferolateral hypokinesis |
| 2 | 20M | Moderna | 2 | >27,000 | 88 | Negative | Down-sloping PR depressions, diffuse ST elevations | LVEF 45%, apical septal hypokinesis |
| 3 | 29M | Moderna | 4 | 6802 | 14 | – | Down-sloping PR depressions, diffuse ST elevations | LVEF 55%, no regional wall motion abnormalities |
| 4 | 30M | Pfizer | 4 | 2518 | 129 | Negative | T-wave inversions in lateral leads | LVEF 65–70%, no regional wall motion abnormalities |
CRP: C-reactive protein.
ECG: electrocardiogram.
TTE: transthoracic echocardiogram.
LVEF: left ventricular ejection fraction.
Coxsackie virus, EBV, CMV.