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. 2021 Jul 28;7(8):e07686. doi: 10.1016/j.heliyon.2021.e07686

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© 2021 Published by Elsevier Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

(A) World-wide Scenario publications on serum alternatives: 1–5 = Africa (01), Ireland (01), Greece (01), Norway (01), Iceland (1), Argentina (01), Mongolia (01), Uruguay (1), Chile (02), Poland (02), Finland (02) and Slovenia (2), New Zealand (2), Australia (03), Thailand (3), Belgium (03), Taiwan (3), South Korea (04), Malaysia (4), Georgia (4), UK (05), Denmark (05), Iran (05) and France (5) = 62; 6–10 = Switzerland (6), Sweden (06), Spain (06) and Portugal (06), Brazil (09), Austria (09) and Canada (10) = 52; 11–15 = India (11), Germany (12), Netherland (12), Japan (14) and Italy (15) = 64; 16–20 = China (16) = 16 and >20 = US (41) = 41. (B) List of publications on alternatives to FBS in cell culture between 2000-2020: The number of publications was gradually increased from the year 2000–2015 and the maximum number of the article published in the recent years from 2016 to 2020. Since the total number of papers so far published in this particular period is 233.