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. 2021 Jun 2;83(7):1161–1166. doi: 10.1292/jvms.20-0519

Fig. 2.

Fig. 2.

Relative mRNA expression of inflammasome sensor subunits in the colonic mucosa of dogs with chronic enteropathy (CE). Expression levels of nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing (NLRP)3 (A and B), NLRP6 (C and D), and NLRP12 (E and F) mRNA were analyzed by real-time PCR in healthy dogs (n=7) and those with CE (n=33), which included dogs with antibiotic-responsive enteropathy (ARE) (n=4), food-responsive enteropathy (FRE) (n=9), and immunosuppressant-responsive enteropathy (IRE)/non-responsive enteropathy (NRE) (n=20). The horizontal lines in each group represent the mean value. Relative mRNA expression was compared between healthy dogs and those with CE by the Mann–Whitney U test (A, C, and E). Relative mRNA expression was compared among healthy dogs and those with ARE, FRE, or IRE/NRE by the one-way ANOVA, followed the Tukey–Kramer test (B), or by the Kruskal-Wallis test, followed the Steel-Dwass test (D and F). *P<0.05, **P<0.01.