Table 2. The correlations between age and mRNA expression levels of inflammasome sensor subunits in the duodenal and colonic mucosae of 42 dogs that included seven healthy dogs and 35 dogs with chronic enteropathy.
| Duodenum (n=42) |
Colon (n=40) |
||||||
|---|---|---|---|---|---|---|---|
| NLRP3a) | NLRP6b) | NLRP12c) | NLRP3 | NLRP6 | NLRP12 | ||
| Age | rs, r value | rs=0.2432 | r=0.1067 | rs=0.4140 | r=0.0833 | rs=0.2861 | rs=0.2016 |
| P value | 0.1207 | 0.1207 | 0.0064 | 0.092 | 0.0735 | 0.2122 | |
The correlations between age and mRNA expression levels of NLRP3 or NLRP12 in the duodenal mucosa and between age and those of NLRP6 or NLRP12 in the colonic mucosa were analyzed by the Spearman’s rank correlation coefficient (rs). The correlations between age and those of NLRP6 in the duodenal mucosa or NLRP3 in the colonic mucosa were analyzed by the Pearson product-moment correlation coefficient (r). a)Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3, b)Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 6, c)Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 12.