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. Author manuscript; available in PMC: 2022 Aug 6.
Published in final edited form as: Circ Res. 2021 Jun 28;129(4):458–470. doi: 10.1161/CIRCRESAHA.121.319163

Figure 3. Transient expression of ADAMTS7 during atherogenesis.

Figure 3.

ADAMTS7 expression reported by the LacZ gene trap tm1b allele in heterozygotes during atherogenesis at 6, 8, 12 and 16 weeks post infection with AAV8-PCSK9. A, Stages examined in the atherogenic model post infection with AAV8-PCSK9. B, Quantitative analysis of β-gal positive cells in the plaque (n=3 to 5 per group, data points represent individual animals). A Kruskal-Wallis test with Dunn’s multiple comparison test was applied, *P<0.05. C-F, Representative photomicrographs of β-gal staining in the aortic sinus at the indicated weeks after AAV8-PCSK9 injection.