Table 1:

Summary of quantitative (left) and qualitative (right) metrics used to evaluate structural MRI data.

Ventricle size (frontal occipital horn ratio, atrial dimension)	Cerebral gray/white matter volume
Thickness of periatrial white matter	Cerebellar atrophy
Gray matter measures (e.g. coronal caudate thickness at the anterior commissure)	Myelination score (adapted from Plecko et. al 16)
Cerebral atrophy (subarachnoid spaces, sulci)	Dysmyelination
Cerebellar volume measures (transverse diameter, width of primary vermian fissure)	Parenchymal injury
Midpons AP dimension17	Metabolic signal abnormality (GP, putamen, thalamus, dentate, subthalamic nucleus)
Corpus callosum measures (genu/splenium thickness, anteroposterior dimension)18	Malformations (e.g. vermian hypoplasia)
Ellipsoid estimate for volume of globus pallidus and dentate signal abnormality	Miscellaneous (e.g. arachnoid cysts, olfactory hypoplasia)