Fig. 1.

Trends in S+ infections in London, February-May 2021. (A) Estimated aggregated weekly incidence (log scale) of symptomatic S+ cases diagnosed via community testing (Pillar 2) calculated by multiplying the fraction of S+ cases by the total number of positives and S+ infections estimated from the ONS infection survey [35]. B) Temporal trends in the proportion of cases and infections that are S+, estimated from symptomatic community testing (Pillar 2), the ONS infection survey, and from SARS-CoV-2 sequence data (COG-UK public data, which may include travelers and surge testing; non-B.1.17 fraction is shown). Shaded ribbons represent 95% uncertainty intervals for the mean. Details on uncertainty intervals can be found in Supplementary Text. Results for other regions of England can be found in Supplementary Figures 1 and 2.