Table 2.

A summary of common diseases/etiologies manifesting predominantly with tremor.

Neurodegenerative

• Parkinson's disease • Essential tremor • Corticobasal syndrome • Progressive supranuclear palsy • Multiple system atrophy

Genetic diseases/mitochondrial diseases

• ANO3 (Anoctamin) mutation or DYT24 • Spinocerebellar ataxia type-12, type 40 • Klinefelter syndrome • Fragile-X tremor ataxia syndrome • Hereditary chin tremor • Charcot-Marie-Tooth disease • Leigh's disease • Mitochondrial polymerase gamma mutation

Metabolic diseases

• Wilson's disease • Hyperthyroidism

Drugs and toxins

• Anti-seizure medications: Phenytoin, valproate • Beta-2 agonists • Thyroid hormone replacement • Dopamine receptor blockers: Neuroleptics, metoclopramide • Lithium • Amiodarone • Chemotherapeutic agents: Tacrolimus, vincristine, cisplatin, methotrexate • Toxins: Mercury, lead, manganese, arsenic, cyanide, carbon monoxide, naphthalene, toluene, lindane

Neuropathic

• Charcot-Marie-Tooth disease • Acute inflammatory polyradiculoneuropathy • Chronic inflammatory polyradiculoneuropathy • Multifocal neuropathy with conduction block • Monoclonal gammopathies

Other causes

Any space occupying lesions, stroke in the basal ganglia or in the cerebello-thalamo-cortical network may result in tremor, albeit along with other focal neurological deficits