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ATG16L1 gene is a direct target of miR 223. (A) The site for miR 223 binding to ATG16L1 was predicted by (http://www.microRNA.org) (http://www.microrna.org/microrna/home.do). (B) miR-223 regulates ATG16L1 expression, as shown by the dual-luciferase reporter assay in 293T cells. Statistically significant differences were determined using the unpaired t-test. Data are presented as means ± SD; *p < 0.05 (n = 3 per group). miR, microRNA; SD, standard deviation.
