FIGURE 2.

CWA protects against LPS-induced gut injury and animal death. (A) Survival was monitored daily for 7 days. (n = 10 mice). (B) Gut permeability was determined by FITC-dextran. FITC (fluorescein isothiocyanate)-dextran recovered from the serum 3 h after oral gavage. (C) H&E images of villous structure, the red border outside the villi indicates brush border which is composed by microvilli. Boxed region indicates magnified view of microvilli. red arrows indicate length of microvilli. (D,E) Representative images of ZO-1 (D) and E-cadherin (E) staining in thin sections of jejunum. (F) Western blot analysis of ZO-1, E-cad, and villin expression in small intestinal tissues. Scale bars, 50 μm. ***P < 0.001, **p < 0.01 by two-sided, unpaired t-test. All data represent at least three independent experiments.