Table 5.
Percentage of porcine pancreas lipase enzyme inhibition and IC50 value.
| Inhibitor | Concentration (μg/mL) | Inhibition Percentage (%) | IC50 Value (μg/mL) |
|---|---|---|---|
| Robusta Green Coffee Beans Extract of NADES-UAE from Optimum condition | 200 | 79.63 + 8.03 | 18.02 |
| 100 | 76.09 + 0.90 | ||
| 50 | 66.25 + 6.36 | ||
| 25 | 50.79 + 6.34 | ||
| 12.5 | 43.52 + 11.22 | ||
| 6.25 | 37.60 + 6.45 | ||
| Robusta Green Coffee Beans Extract of Reflux Method | 200 | 39.57 + 2.51 | >200 |
| 100 | 32.05 + 7.81 | ||
| 50 | 28.53 + 7.94 | ||
| 25 | 22.30 + 8.50 | ||
| 12.5 | 18.91 + 1.37 | ||
| 6.25 | 14.59 + 10.43 | ||
| Orlistat | 200 | 93.29 + 4.60 | 8.86 |
| 100 | 89.41 + 10.27 | ||
| 50 | 77.31 + 7.20 | ||
| 25 | 55.57 + 9.95 | ||
| 12.5 | 52.38 + 2.33 | ||
| 6.25 | 50.60 + 11.39 | ||
| Caffeine Standard | 200 | 83.88 + 2.08 | 15.59 |
| 100 | 81.44 + 2.08 | ||
| 50 | 76.19 + 1.78 | ||
| 25 | 64.60 + 6.59 | ||
| 12.5 | 38.64 + 0.88 | ||
| 6.25 | 34.04 + 3.18 | ||
| CGA Standard | 200 | 89.63 + 0.44 | 11.90 |
| 100 | 86.74 + 2.75 | ||
| 50 | 77.57 + 1.82 | ||
| 25 | 64.23 + 0.02 | ||
| 12.5 | 59.23 + 0.40 | ||
| 6.25 | 29.43 + 2.72 | ||
| NADES Solution | Pure | -29.40 + 8.84 | - |
| 100 | -30.14 + 2.11 |