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. 2021 Aug 9;12:111. doi: 10.1186/s13244-021-01053-y

Table 1.

Italian consensus statement AIT, AME, SIE and SIAPEC-IAP for the classification and reporting of thyroid cytology [16, 17]

Code Diagnostic category Risk of malignancy Management
TIR 1 Non-diagnostic Not determinated Repeat US-guided FNAB
TIR 1C Non-diagnostic cystic Low risk Evaluate clinical context and eventually repeat US-guided FNAB
TIR 2 Non-malignant (benign)  < 3% Follow-up
TIR 3A Low risk indeterminate  < 10% Repeat FNAB/ Follow-up
TIR 3B High risk indeterminate 15–30% Surgical excision
TIR 4 Suspicion of malignancy 60–80% Surgical excision with intraoperative examination
TIR 5 Malignant 95% Surgical excision with diagnostic in-depth in selected cases (metastasis, lymphoma)