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. 2021 Jul 26;12:665881. doi: 10.3389/fphar.2021.665881

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Copyright © 2021 Shin, Bose, Choi, Kim, Chin, Song, Nam and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of PN and FPN on the lipid metabolism of HFD-induced mouse model after treatment for 9 weeks. The TG was measured in (A) serum and (D) liver. The expression of the genes of interest in the liver, hypothalamus, and adipose tissue was determined by RT-PCR. The relative gene expressions of (B) PPAR-γ and (C) LPL which play an important role in lipid metabolism were measured. The data are expressed as the mean ± SEM (n = 7–8); #p < 0.05; ###p < 0.001; NOR vs. HFD group. *p < 0.05; **p < 0.01; ***p < 0.001; HFD group vs. treatment groups (XEN, PN and FPN).