Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 26;12:665881. doi: 10.3389/fphar.2021.665881

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Shin, Bose, Choi, Kim, Chin, Song, Nam and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of PN and FPN on the gene expression of inflammatory mediators and antimicrobial peptides in a HFD-induced mouse model after treatment for 9 weeks. Expressions of the genes of interest in the intestine, liver, and adipose were determined by RT-PCR. The relative gene expression of the inflammatory mediators (A) TNF-α, (B) MCP-1, and (C) IL-1β as well as relative gene expressions of anti-microbial peptides (D) Pgc1α, (E) Pla2g2α, and (F) Reg3γ were measured in the colon tissue. The relative gene expressions of LPS binding protein (LBP) was measured in (G) colon, (H) liver, and (I) adipose tissue. The data are expressed as the mean ± SEM (n = 7–8); #p < 0.05; ##p < 0.005; ###p < 0.001; NOR vs. HFD group. *p < 0.05; **p < 0.01; ***p < 0.001; HFD group vs. treatment groups (XEN, PN and FPN).