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. 2021 Jul 26;11:735447. doi: 10.3389/fonc.2021.735447

Figure 6.

Figure 6

miR-4277 enhances the antitumor effect of sorafenib in a nude mouse model. MHCC97-H cells were transfected with vectors (control miR, miR-4277, or miR-4277 + CYP3A4Mut) and subcutaneously injected into nude mice. The mice then received the indicated dose of sorafenib via oral administration. The results are shown as tumor images (A), tumor volumes (B), or tumor weights (C). *P < 0.05.