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. 2021 Aug 5;41(8):BSR20210953. doi: 10.1042/BSR20210953

Figure 1. The link between cellular lipid metabolism and systemic lipid homeostasis is not clear.

Figure 1

SARS-CoV-2 infects host cells and hijacks lipid metabolism for replication. In the innate immune cells like macrophages synthesis of TGs are induced and these cells secrete TGs, cholesterol, and PLs in response to the blood levels of HDL and ApoA1. How these changes at the cellular level are translated to the systemic lipid metabolism and blood levels of TGs, FC, PLs, HDL, VLDL, and ApoA1 during SARS-CoV-2 infection is not clear.