Table 1. List of various biosensors developed for the detection of Covid-19.
Sl. No. | Biosensor type | Sample vol. (µl) | LOD | Sensitivity (%) | Reference |
---|---|---|---|---|---|
1 | Electrochemical | - | 15 fM | - | [115] |
90 fM | - | [116] | |||
2 | Chip-based | 10 | 30–1000 CFU/ml | - | [117] |
3 | Paper-based | 20 | - | 91.54 | [118] |
10 | 1 ng/ml | >90 | [119] | ||
4 | Film-based | 500 | 30 CFU/ml | - | [120] |
5 | 2D material based | 5 | 0.01 CFU/ml | - | [121] |
6 | Real-time qRT-PCR | 5 | 3.2 copy/µl | - | [122] |
7 | LAMP | - | - | - | [123] |
8 | CRISPR-based LAMP with LFA | <10 µl | 10 copy/µl | 95% | [124] |
9 | RT-LAMP | 25 µl | 20 copy/reaction | 100% | [125] |
10 | RCA with MNP | - | Sub-fM | - | [126] |
11 | Isothermal DNA amplification | - | - | 95% | [127] |
12 | LAMP with colorimetric read out | 20 µl | 4.8 copy/µl | - | [128] |
Abbreviations: CFU, colony forming unit; fM, femtomolar; LOD, limit of detection; RT, reverse transcription.