Table 3.
Results of the univariate meta-regression analyses by adaptation and symptomatic variables.
ASD SS | Compositee | DLS | Social | |||||
---|---|---|---|---|---|---|---|---|
Coeff | P | Coeff | P | Coeff | P | Coeff | P | |
Internal Validity | ||||||||
Risk of biasa | 1.100 | 0.33 | 0.450 | 0.16 | 0.019 | 0.97 | 0.780 | 0.03* |
Sample size | 0.020 | 0.41 | −0.014 | 0.15 | −0.037 | 0.63 | −0.033 | 0.62 |
Population Characteristics | ||||||||
Pre age | −0.080 | 0.17 | −0.018 | 0.48 | −0.046 | 0.46 | −0.027 | 0.61 |
Pre IQ | −0.029 | 0.75 | 0.001 | 0.98 | −0.014 | 0.74 | 0.011 | 0.83 |
Time intervalb | −0.002 | 0.85 | −0.002 | 0.65 | 0.009 | 0.53 | –0.022 | 0.03* |
Post agec | −0.005 | 0.64 | −0.001 | 0.89 | 0.0006 | 0.98 | −0.039 | 0.05 |
Intervention Characteristics | ||||||||
Approachesd | –1.310 | <0.05* | −0.704 | 0.18 | −0.550 | 0.30 | 0.330 | 0.47 |
Total treatment hours | −0.0002 | 0.19 | 0.0001 | 0.02* | −0.0001 | 0.82 | 0.0002 | 0.03* |
Intensity | −0.071 | 0.06 | 0.047 | <0.01* | 0.048 | 0.35 | 0.087 | 0.03* |
Duration | −0.021 | 0.40 | 0.025 | 0.05 | −0.014 | 0.50 | 0.026 | 0.10 |
Delivery agents | 1.180 | 0.15 | 0.097 | 0.77 | 0.120 | 0.84 | 0.033 | 0.95 |
Categorical variable, strong = 1, non-strong (adequate and weak) = 0.
Time interval between postintervention and follow-up.
Mean age of participants at last assessment.
Categorical variable, EIBI = 1, non-EIBI (ESDM and other interventions) = 0.
Based on the result of sensitivity analysis, Magiati et al. (20) was removed from the meta-regression analyses.
ASD SS, ASD symptom severity; Coeff, unstandardized meta-regression coefficient; Composite, Vineland adaptive composite score; DLS, Daily living skills; Pre, preintervention.
ASD SS: Weiss and Delmolino (46); Smith et al. (43); Magiati et al. (20); Perry et al. (48); Vinen et al. (45); Clark et al. (36); Landa and Kalb (41).
Composite: Sallow and Graupner (42); Howard et al. (40); Cohen et al. (37); Smith et al. (43); Kovshoff et al. (47); Weiss and Delmolino (46); Bibby et al. (35); Smith et al. (43); Perry et al. (48); Estes et al. (13).
DLS and Social: Sallow and Graupner (42); Howard et al. (40); Cohen et al. (37); Smith et al. (44); Kovshoff et al. (47); Estes et al. (13); Akshoomoff et al. (34).
p < 0.05.
ASD symptom severity - Approaches: Adj R2 = 64.19%. Vineland adaptive composite score - Total treatment hours: Adj R2 = 78.06%. Vineland social adaptive score - Total treatment hours: Adj R2 = 100.00%. Vineland social adaptive score - risk of bias: Adj R2 = 100.00%. The bold values represents the p value < 0.05.