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. 2021 Jul 26;12:711484. doi: 10.3389/fendo.2021.711484

Table 3.

Features of the study population according to the presence of cardiovascular disease (CVD).

CVD - (n=2363) CVD + (n=371) p-value
Age (years) 57.8 ± 0.4 66.7 ± 0.7 <0.001
Male sex (%) 45.3 ± 1.0 58.3 ± 4.1 0.010
Race-Ethnicity (%) 0.006
 Non-Hispanic white 66.2 ± 2.9 74.3 ± 3.5
 Hispanic 13.9 ± 1.9 7.7 ± 1.5
 Non-Hispanic black 9.9 ± 1.6 9.7 ± 1.9
 Non-Hispanic Asian 5.7 ± 1.0 2.0 ± 0.6
 Other 4.3 ± 0.7 6.3 ± 2.2
Cigarette smoke (%) <0.001
 Never 60.0 ± 1.8 41.5 ± 4.2
 Past 28.4 ± 1.2 41.4 ± 3.3
 Current 11.6 ± 1.1 17.1 ± 2.9
BMI (Kg/m2) 30.0 ± 0.3 30.1 ± 0.4 0.601
Laboratory parameters
HbA1c (%) 5.8 ± 0.0 6.2 ± 0.1 <0.001
AST (IU/L) 20.9 ± 0.2 21.4 ± 0.7 0.443
ALT (IU/L) 21.6 ± 0.3 20.5 ± 1.0 0.282
GGT (IU/L) 28.2 ± 0.7 34.1 ± 3.3 0.080
Albumin (g/dL) 4.1 ± 0.0 4.0 ± 0.0 <0.001
Platelet count (109/L) 242.7 ± 3.6 221.1 ± 4.2 <0.001
Total Cholesterol (mg/dL) 198.4 ± 2.0 176.6 ± 5.2 0.001
Triglycerides (mg/dL) 150.3 ± 3.7 164.1 ± 7.7 0.058
HDL-Cholesterol (mg/dL) 54.2 ± 0.5 51.2 ± 1.8 0.148
Comorbidities
Type 2 diabetes (%) 16.7 ± 0.9 39.3 ± 3.1 <0.001
Blood pressure category (%) 0.001
 Optimal 26.8 ± 2.3 12.6 ± 3.1
 Normal 14.3 ± 1.0 9.3 ± 2.2
 High-normal 9.2 ± 1.3 7.1 ± 1.7
 Hypertension 49.7 ± 2.3 71.0 ± 5.3
CKD (%) 8.6 ± 0.8 25.2 ± 2.9 <0.001
Statin use (%) 21.7 ± 1.7 65.9 ± 3.6 <0.001
CAP ≥ 274 dB/m 47.1 ± 1.5 59.6 ± 3.8 0.013
LSM ≥ 8 kPa 9.3 ± 0.8 12.9 ± 2.4 0.123

Data are expressed as weighted proportions [± Standard Error (SE)] for categorical variables and as weighted means ± SE for continuous variables. Linear regression and Rao-Scott chi-square test were used to compare groups.

BMI, Body Mass Index; HbA1c, Hemoglobin A1c; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyltranspeptidase; HDL, high density lipoprotein; CKD, chronic kidney disease.