Table 3.
The clinical application of personalized neoantigen-pulsed DC vaccines.
| Tumor types | Phase | Status | Participants | Source of DCs | NCT number |
|---|---|---|---|---|---|
| Breast Cancer | Phase I | Completed | 9 | monocytes | NCT04879888 |
| Triple Negative Breast Cancer | Phase I | Recruiting | 5 | / | NCT04105582 |
| Gastric Cancer | Phase I | Recruiting | 80 | / | NCT04147078 |
| Hepatocellular Carcinoma | |||||
| Non-Small-Cell Lung Cancer | |||||
| Colon Rectal Cancer | |||||
| Pancreatic Adenocarcinoma | Phase Ib | Recruiting | 12 | PBMC | NCT04627246 |
| Non-Small-Cell Lung Cancer | Phase I | Recruiting | 6 | monocytes | NCT04078269 |
| Advanced Biliary Tract Tumor | Phase I/II | Recruiting | 40 | / | NCT02632019 |
| Non-Small-Cell Lung cancer | Phase I | unknown | 20 | / | NCT02956551 |
| Liver Cancer | Phase I | unknown | 24 | / | NCT03674073 |
| Non-Small-Cell Lung cancer | Phase I | unknown | 30 | / | NCT03871205 |
| Glioblastoma | Phase I | Enrolling by invitation | 10 | / | NCT03914768 |
| Colorectal Cancer | Phase I/II | Active, not recruiting | 25 | / | NCT01885702 |
| Non-Small-Cell Lung cancer | Phase I/II | Not yet recruiting | 20 | peripheral blood | NCT03205930 |