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. 2021 Jul;9(14):1148. doi: 10.21037/atm-21-2589

Figure 2.

Figure 2

The frequency of M-MDSCs in peripheral blood of cancer patients and healthy donors. (A) CD14+HLA-DR M-type MDSCs were significantly elevated in patients relative to healthy donors (mean 9.01% vs. 2.63%, P<0.0001). (B) A significant positive correlation was observed between healthy donors and patients with different stage (mean 2.06% vs. 7.55%, 9.97% and 10.17% for healthy vs. stage I, II and III; P<0.0001, P<0.0001, P<0.0001 respectively). No correlation between the M-MDSCs and TNM stage (C) or tumor differentiation (D) stage. * indicates a P value of <0.05; *** indicates a P value of <0.0001. MDSCs, myeloid-derived suppressor cells; M-MDSCs, monocytic myeloid-derived suppressor cells; TNM, tumor, node, metastasis; Health, healthy volunteers; Patients, HNSCC patients.