Table 2. The evaluation of the HAV sequencing-based surveillance in sentinel provinces, 2019–2020.
| Aspects | Indicator definition | Indicator measurement | Indicator value | Score† | Performance |
|---|---|---|---|---|---|
| Data quality | 1.75 | Weak | |||
| (I) Met NRDSS case definition | % of HepA cases | 79.41 | 2 | ||
| (II) Serum samples for sequencing | % of cases obtained serum samples | 77.45 | 2 | ||
| (III) Samples sequenced | % of samples with detectable HAV RNA | 49.79 | 1 | ||
| (IV) Completeness of case information | % of forms with complete data | 75.10 | 2 | ||
| Timeliness | 1.75 | Weak | |||
| (I) Cases reported per NRDSS time requirement | % of cases reported within 24 hours | 50.98 | 1 | ||
| (II) Timely sample collection | % of samples were collected within 3 days | 75.49 | 2 | ||
| (III) Samples timely transferred to central CDC lab | % of samples transferred to central CDC within one month | 47.36 | 1 | ||
| (IV) Timely sequencing and sharing | <1 month: 83.331 to 2 months: 16.67 >2 months: 0.0 |
3‡ | |||
| Acceptability | 2 | Moderate | |||
| (I) Acceptable to patients | % of PHPs never be rejected by patients | 17.24 | 1 | ||
| (II) Acceptable to physicians from sentinel hospital | % of PHPs never fail to contact discharged patients due to delayed reporting | 72.41 | 2 | ||
| (III) Acceptable to PHP | % of PHPs within each category [not satisfied (NS), poorly satisfied (PS), satisfied (S), very satisfied (VS)] | VS: 66.52 S: 34.48 PS: 0.0 NS: 0.0 |
3§ | ||
| Utility | 2.33 | Moderate | |||
| (I) Detecting genomic clusters in lab | Eleven clusters were detected | 3 | |||
| (II) Sharing of HAV sequencing with CDCs | Sequence data were available in two provinces | 1 | |||
| (III) CDC investigation and outbreak control | One outbreak was detected and managed promptly | 3 |
†A scale from 1 to 3 was used to provide a score for indicators as follows: <60% scored 1 (weak performance); 60–79% scored 2 (moderate performance); ≥80% scored 3 (good performance), the score for each aspect was the mean score of its indicators. ‡The combined percentage of “one month” and “one to two months” was used to obtain the score. §The combined percentage of “very satisfied” and “satisfied” was used to obtain the score. HepA, hepatitis A; HAV, hepatitis A virus; RNA, ribonucleic acid; PHPs, public health practitioners; CDC, Centers for Disease Control and Prevention.