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Ca2+ signals evoked by dilute solutions of a Zn2+/PGE1 mixture. (A) Representative Ca2+ signals in human sperm stimulated with a serially diluted mixture of 10 μM PGE1 and 1 mM Zn2+. (B) Concentration–response relationship for the maximal amplitudes of Ca2+ signals shown in (A) relative to that evoked by PGE1 (3 μM) in the absence of Zn2+ (set to 1).
