TABLE 2.
Clinical characteristics based on onset age
| Young Onset | Versus | Adult Onset | χ2 or t | P | |
|---|---|---|---|---|---|
| Number of participants | 81 | 286 | |||
| Female | 44 (54%) | 166 (58%) | 0.3 | 0.566 | |
| Mean age of onset, y | 11.6 ± 5.3a | 44.9 ± 12.9a | −34.4 | <0.001 | |
| Dystonia duration, y | 31.6 ± 17.2a | 13.3 ± 10.6* | 9.1 | <0.001 | |
| Task specificity | 37 (45%)a | 208 (73%)a | 21.2 | <0.001 | |
| Sensory trick | 34 (42%) | 119 (42%) | 0.001 | 0.972 | |
| BFM total | 15.8 ± 14.8a | 8.6 ± 9.3a | 4.1 | <0.001 | |
| Focal onset | 71 (86%) | 221 (76%) | 4.2 | 0.040 | |
| Spread after onset | 41 (49%)a | 56 (19%)a | 25.2 | <0.001 | |
| Onset, dominant limb | 64 (79%) | 238 (84%) | 0.9 | 0.347 | |
| Focal | 27 (33%) | 160 (56%) | |||
| Segmental | 22 (27%) | 92 (32%) | |||
| Multifocal | 12 (15%) | 18 (6%) | |||
| Generalized | 19 (23%) | 14 (5%) |
a
significant differences across onset age subgroups.
Young (age <21 years) onset and adult (age ≥21). Pearson χ2 or t statistic are reported for nominal or continuous group comparisons, respectively. Percentage focal onset and spread after onset reflect a percentage of upper limb onset, whereas all other percentages reflect the percentage of participants in young versus adult onset. Significant results appear in bold font. Data are n (%) or mean ± standard deviation.
BFM, Burke-Fahn-Marsden scale.