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. 2021 Jul 26;9:691634. doi: 10.3389/fpubh.2021.691634

Table 3.

Estimated number of HPV-attributable cancer deaths in the United States in 2017 and estimated YPLL associated with HPV-attributable cancer stratified by sex and HPV type.

Total Women Men
Cervix Vagina Vulva Anus Oropharynx Penis Anus Oropharynx
Estimated deathsa
Any HPV 7,085 3,812 308 868 677 182 223 388 628
High-risk HPV types targeted by 9vHPVb 6,482 3,403 302 793 661 173 200 362 588
Estimated YPLL
Any HPV 154,954 100,998 4,405 12,247 12,548 3,249 3,377 7,223 10,905
High-risk HPV types targeted by 9vHPVb 141,019 90,185 4,311 11,179 12,249 3,095 3,036 6,751 10,212
Estimated YPLL per death 22 26 14 14 19 18 15 19 17

9vHPV, nonavalent HPV vaccine; HPV, human papillomavirus; YPLL, years of potential life lost.

a

HPV-attributable cancer deaths were calculated based on CDC WONDER-reported total US cancer deaths per type in 2017 (i.e., 4,207 cervical; 1,262 vulvar; 411 vaginal; 352 penile; 1,169 anal; 1,154 oropharyngeal).

b

HPV 16, 18, 31, 33, 45, 52, and 58.