TABLE 1.
Participants | Age | Sex | Stimulated eye (fMRI) | Visual acuity | Visual field (MD—dB) | Fixation stability1 (2°) | Onset age (yrs) | Duration (yrs) |
GL1 | 68 | Female | Left | 1.0 | −13.9 | 100% | 59 | 9 |
GL2 | 70 | Male | Left | 0.4 | −25.8 | 100% | 65 | 5 |
GL3 | 51 | Female | Right | 0.8 | −32.5 | na | 48 | 3 |
GL4 | 72 | Male | Left | 0.8 | −30.7 | 100% | 47 | 25 |
RP1 | 56 | Female | Left | 0.6 | −23.5 | 97% | 26 | 30 |
RP22 | 78 | Male | Left | 0.05 | −30.7 | 99% | 59 | 19 |
RP3 | 46 | Female | Right | 0.05 | −27.3 | 31% | 11 | 34 |
HC1 | 64 | Male | Left | 1.6 | 1.0 | na | na | na |
HC2 | 79 | Female | Left | 1.3 | 0.0 | na | na | na |
HC3 | 56 | Male | Left | 1.3 | 0.0 | na | na | na |
HC4 | 73 | Male | Left | 1.0 | −0.9 | na | na | na |
HC5 | 75 | Male | Left | 1.3 | 0.0 | na | na | na |
HC6 | 71 | Female | Right | 1.0 | −1.4 | na | na | na |
HC7 | 63 | Female | Left | 1.0 | na | na | na | na |
GL, glaucoma; RP, retinitis pigmentosa; HC, control participants; MD, Visual field mean deviation as measured with standard automated perimetry (SAP); na, not available.
1Proportion of central fixations within a fixation window of 2° radius as determined with a fundus-controlled perimeter (see section “Materials and Methods.”).
2RP participant with secondary glaucoma; visual field defects are predominantly driven by the primary disease, i.e., RP, consequently, RP2 is classified as RP.