Table 1.
Laboratory Results
| Laboratory Test | Result | Reference Range |
|---|---|---|
| ANA titer, pattern | 1:80, speckled | |
| Complement C3, mg/dL | 100 | 75-170 |
| Complement C4, mg/dL | 27 | 10-40 |
| Cytoplasmic ANCA titer | <1:40 | |
| Perinuclear ANCA titer | <1:40 | |
| Anti-GBM IgG, AI | <1.0 | <1.0 |
| Rheumatoid factor, IU/mL | <10 | 0-14 |
| Hepatitis B surface antigen | Not detected | |
| Hepatitis B surface antibody | Nonreactive | |
| Hepatitis B core antigen | Not detected | |
| Hepatitis B core antibody | Nonreactive | |
| Hepatitis C antibody | Nonreactive | |
| HIV 1,2 antigen/antibody | Nonreactive | |
| Syphilis antibody | Negative | |
| Cryoglobulin | Negative | |
| Serum protein electrophoresis | ||
| Total protein, g/dL | 5.5 | 6.4-8.9 |
| Albumin, g/dL | 3.2 | 3.5-5.7 |
| Interpretation | No restricted bands seen in the γ region | |
| Serum immunofixation | Possible monoclonal free λ light chain | |
| Random urinary protein electrophoresis | ||
| Urinary protein, mg/dL | 353 | 0-10 |
| Urinary albumin, mg/dL | 223.5 | 0-10 |
| Interpretation | Restricted band seen in the γ region | |
| Random urine immunofixation | Monoclonal free λ light chain | |
| Serum free light chains | ||
| Free κ light chain, mg/dL | 3.47 | 0.33-1.94 |
| Free λ light chain, mg/dL | 17.1 | 0.57-2.63 mg/dL |
| Free κ:λ light chain ratio | 0.20 | 0.26-1.65 |
Abbreviations: ANA, antinuclear antibody; ANCA, antineutrophil cytoplasmic antibody; GBM, glomerular basement membrane; IgG, immunoglobulin G.