Table 2.
Cox Proportional Hazards Model for the Primary Outcome of CKD Incidence, Progression, Kidney Failure With Replacement Therapy, or Death
| Patient Characteristics (N = 1,231) | aHRa | 95% CI | aHRb | 95% CI |
|---|---|---|---|---|
| AKD stage at hospital discharge or within 90 d | ||||
| Stage 0C vs 0A | 1.76 | 1.33-2.32 | 1.74 | 1.32-2.29 |
| Stage ≥1 vs 0A | 3.01 | 2.29-3.96 | 3.25 | 2.52-4.20 |
| Stage ≥1 vs 0C | 1.72 | 1.30-2.26 | 1.87 | 1.44-2.43 |
| Age, 10-y | 1.09 | 1.01-1.17 | 1.09 | 1.01-1.17 |
| Man vs woman | 0.96 | 0.77-1.19 | — | — |
| Black vs other | 1.23 | 0.99-1.52 | 1.23 | 1.00-1.53 |
| Anemia | 1.69 | 1.18-2.42 | 1.69 | 1.18-2.41 |
| Diabetes | 1.00 | 0.78-1.28 | — | — |
| Log-transformed baseline eGFR | 0.87 | 0.67-1.14 | — | — |
| AKI severity | ||||
| AKI severity KDIGO 2-3 vs 1 | 1.37 | 0.99-1.90 | — | — |
| AKI severity KDIGO 3D vs 1 | 1.16 | 0.90-1.48 | — | — |
| SOFA score ≥ 4 vs <4 | 1.36 | 1.09-1.70 | 1.41 | 1.14-1.76 |
Abbreviations: aHR, adjusted hazard ratio; AKD, acute kidney disease; AKI, acute kidney injury; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; KDIGO, Kidney Disease: Improving Global Outcomes; SOFA, Sequential Organ Failure Assessment.
a
Initial model.
b
Final model after backward selection.