Figure 3.

Pre-treatment and preoperative CT or MR scans and H&E of resected regimen. (A) Pre-treatment MR or CT scans revealed that the patients had extrahepatic metastasis lesions. After stereotactic treatment, these metastatic lesions disappeared. (B) A representative case. Patient 9 was diagnosed with a solitary HCC and with an oligometastasis in lower abdominal cavity (BCLC stage C) and received TACE, radiotherapy, lenvatinib 8 mg/day and toripalimab 240 mg every 3 weeks. Four weeks later, the conventional operation was performed. H&E staining of the surgically resected specimen showed a pCR. HCC, hepatocellular carcinoma; BCLC, Barcelona Clinic Liver Cancer; TACE, transarterial chemoembolization; H&E, hematoxylin and eosin; pCR, pathological complete response.