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. 2021 Aug;10(4):498–506. doi: 10.21037/hbsn-20-846

Table 5. Most common grade 3–4 adverse events occurring in more than 5% of patients in the safety population.

mFOLFIRINOX grade 3–4, n (%) GEMOX grade 3–4, n (%) P value
Event 12 (48.0) 7 (36.8) 0.459
Hematological
   Neutropenia 7 (28.0) 3 (15.8)
   Thrombocytopenia 2 (8.0) 4 (21.1)
   Anemia 3 (12.0) 2 (10.5)
Non-hematological
   Nausea 2 (8.0) 1 (5.3)
   Vomiting 2 (8.0) 2 (10.5)
   Anorexia 1 (4.0) 1 (5.3)
   Diarrhea 4 (16.0) 1 (5.3)
   Fatigue 3 (12.0) 2 (10.5)
   Peripheral Neuropathy 2 (8.0) 4 (21.1)