Table 2.
Clinical outcomes after the propensity-score matching.
| Characteristic | Total N = 300 |
Non-probiotics group n = 150 |
Probiotics group n = 150 |
Difference | p value |
|---|---|---|---|---|---|
| Primary outcome | |||||
| Time to clinical improvement, days | 20.0 (15.0–28.0) | 21.0 (17.0–29.0) | 18.0 (14.0–28.0) | –3 (–4 to –1) | 0.022 |
| Secondary outcomes | |||||
| Hospital stay, days | 21.0 (15.0–28.0) | 22.0 (16.0–31.0) | 19.0 (15.0–25.0) | –3 (–5 to –1) | 00.009 |
| Duration of viral shedding, days | 16.0 (12.0–22.0) | 18.0 (13.0–24.0) | 15.0 (10.0–20.0) | –3 (–6 to –1) | <0.001 |
| Duration of fever, days | 7.0 (4.0–9.0) | 7.0 (4.0–10.0) | 6.0 (3.0–9.0) | –1.0 (–2.0 to 0.0) | 00.025 |
| ICU stay, days | 15.0 (10.0–20.0) | 16.0 (13.0–30.0) | 13.0 (7.0–17.0) | –4 (–9 to 2) | 0.397 |
| Duration of NIMV, days | 6.0 (4.75–8.0) | 6.0 (4.0–8.0) | 7.0 (5.0–9.5) | 1 (–1 to 3) | 0.545 |
| Duration of IMV, days | 19.0 (10.5–28.5) | 24.0 (19.0–33.0) | 12.0 (7.0–25.5) | –11 (–20 to 1) | 0.615 |
| Oxygen support, days | 14.0 (8.0–21.0) | 14.5 (7.25–20.0) | 14.0 (8.0–21.0) | 0 (–3 to 2) | 0.081 |
Data are median (interquartile range).
ICU, intensive care unit; IMV, invasive mechanical ventilation; NIMV, non-invasive mechanical ventilation.