Table 4.
Demographic and clinical presentations of MRSA and V. vulnificus associated necrotizing fasciitis patients
| Characteristics | MRSA (N-16) |
Vibrio vulnificus (N-40) |
p-value |
|---|---|---|---|
| Age (years) | |||
| Mean | 62.8 | 71.2 | 0.35 |
| Gender | |||
| Female | 5 | 14 | 0.52 |
| Male | 11 | 26 | |
| Comorbidities (%) | |||
| Hepatic dysfunction | 5 (31.2) | 25 (62.5) | 0.034* |
| LC alone or with others | 3 (18.75) | 7 (17.5) | 1 |
| Diabetic mellitus | 8 (50) | 12 (20) | 0.136 |
| Cancer | 2 (12.5) | 2 (5) | 0.321 |
| Chronic kidney disease | 4 (25) | 10 (25) | 0.624 |
| Interval from contact or injury | 5.5 | 1.2 | 0.023* |
| to presentation at ER (days) | |||
| Interval from diagnosis at ER | 5.8 | 4.7 | 0.53 |
| to first operation (hours) | |||
| Wound location (%) | |||
| Upper extremity | 8 (50) | 24 (60) | 0.489 |
| Lower extremity | 8 (50) | 16 (40) | |
| Outcome | 6.25% | 10% | |
| Death | 1 | 4 | 0.383 |
| Survivors | 15 | 36 | |
| Related events (%) | |||
| Seawater or seafood contact | 2 (12.5) | 37 (92.5) | 0.001* |
| Farm/dirty-water contacted | 1 (6.25) | 3 (7.5) | 0.43 |
| Vital signs (%) | |||
| Body temperature > 38 °C | 4 (25) | 8 (20) | 0.376 |
| Heart rate ≥ 100 | 10 (62.5) | 22 (55) | 0.607 |
| Respiratory rate > 20 | 7 (43.75) | 23 (57.5) | 0.325 |
| Systolic blood pressure < 90 | 0 | 9 (22.5) | 0.036* |
| Cultures (%) | |||
| Blood (P) Wound (P) | 3 (18.75) | 15 (37.5) | |
| Blood (P) Wound (N) | 0 | 11 (27.5) | |
| Blood (N) Wound (P) | 13 (81.25) | 14 (35) | |
| Presence of bacteremia (%) | 3 (18.75) | 26 (65) | 0.002* |
Blood (P), culture-positive blood sample; Blood (N), culture-negative blood sample; Wound (P), culture-positive surgical wound sample; Wound (N), culture-negative surgical wound sample
Hepatic dysfunction included liver cirrhosis (LC), hepatitis B or C, hepatocellular carcinoma, and alcoholic liver disease
*Mean p < 0.05 and the difference was significant