Table 2.
Factors associated with severe COVID-19 in the derivation cohort (univariate logistic regression).
| Characteristics | OR (95% CI) | P value |
|---|---|---|
| Sex, Male vs. Female | 1.42 (0.81–2.54) | 0.218 |
| Age (years) | 1.07 (1.05–1.09) | <0.001 |
| Time from onset to admission (days) | 1.07 (1.01–1.13) | 0.031 |
| Fever, Yes vs. No | 2.11 (1.10–4.42) | 0.024 |
| Cough, Yes vs. No | 2.01 (1.13–3.75) | 0.018 |
| Dyspnea, Yes vs. No | 14.52 (1.16–460.18) | 0.039 |
| CCI, ≥1 vs. 0 | 2.95 (1.53–5.51) | 0.002 |
| WBC (109/L) | 0.96 (0.82–1.12) | 0.595 |
| Lymphocyte count (109/L) | 0.04 (0.02–0.10) | <0.001 |
| Platelet count (109/L) | 0.99 (0.99–1.00) | 0.001 |
| Creatinine (umol/L) | 1.01 (1.00–1.02) | 0.165 |
| C-reactive protein (mg/L) | 1.02 (1.01–1.03) | <0.001 |
| Procalcitonin (ng/mL) | 1.03 (0.98–1.07) | 0.244 |
| D-dimer (mg/L) | 1.33 (1.11–1.59) | 0.002 |
| Pulmonary opacity score (%) | 1.07 (1.05–1.08) | <0.001 |
Abbreviations: OR, odds ratio; CI, confidence interval; CCI, Charlson comorbidity index; WBC, white blood cell.