Table 1.
Average accuracy, precision, and recall afforded by the ML classifiers in separate experiments.
| KNN | NB | GB | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Acc | Prc | Rec | Acc | Prc | Rec | Acc | Prc | Rec | |
| S. typh. | 1.00 | 1.00 | 1.00 | 0.99 | 0.96 | 1.00 | 0.99 | 0.96 | 1.00 |
| K. aero. | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||
| OR:H48:K | 1.00 | 1.00 | 1.00 | 0.95 | 1.00 | 0.96 | |||
| OR:H48:K | 1.00 | 1.00 | 1.00 | 0.98 | 1.00 | 0.96 | 1.00 | 1.00 | 1.00 |
| O157:H7 | 1.00 | 1.00 | 0.96 | 1.00 | 1.00 | 1.00 | |||
| BY4741 | 0.88 | 1.00 | 0.88 | 0.85 | 0.75 | 0.75 | 0.96 | 0.89 | 1.00 |
| set1Δ | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||
| trf4Δ | 0.73 | 1.00 | 0.80 | 1.00 | 1.00 | 0.88 | |||
| rit1Δ | 1.00 | 0.71 | 1.00 | 0.71 | 1.00 | 1.00 | |||
| HeLa | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| HEK 293T | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||
| U-251 MG | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||
| astrocytes | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| microglia | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||
| neurons | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |||
Differentiation of a) members of the Enterobacteriaceae family (i.e., S. typhimurium, K. aerogenes, and E. coli OR:H48:K, each with testing N = 8); b) E. coli serotypes (i.e., OR:H48:K and O157:H7, N = 8 ea.); c) wildtype and deletion mutants of S. cerevisiae (i.e., BY4741, trf4Δ, and rit1Δ N = 8 ea., set1Δ N=3); d) immortalized human cell lines from different organs (i.e., HEK 293T and HeLa N = 8 ea., and U-251 MG N = 10); and e) primary human cell lines from the central nervous system (i.e., astrocytes N = 3, microglia N = 15, and neurons (N = 5). N indicates the number of rPTM profiles utilized exclusively during the testing phase (i.e., 30% of the entire set available for each class, see Experimental).