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. 2021 Aug 9;21:388. doi: 10.1186/s12903-021-01749-z

Table 2.

Differences in adjusted value (mean ± standard error) of S100A8 (pg/ml) and S100A9 (pg/ml) by periodontitis status (n = 149)

Protein Periodontitis status p value
Sample No-Stage I (n = 50) Stage II (n = 76) Stage III–IV (n = 23)
S100A8 (pg/ml)
Saliva 5348.53 ± 794.80a 8152.65 ± 607.91b 9512.13 ± 1132.64b 0.007
GCF 416.43 ± 56.02a 146.84 ± 42.85b 187.40 ± 79.84b 0.002
Blood 497,523.22 ± 35,568.06 579,163.20 ± 27,204.67 648,641.67 ± 50,687.01 0.057
S100A9 (pg/ml)
Saliva 1430.58 ± 393.97 1380.99 ± 301.33 1780.66 ± 561.44 0.820
GCF 230.12 ± 36.41a 98.17 ± 27.85b 63.59 ± 51.89b 0.011
Blood 162,405.26 ± 4146.13 172,167.34 ± 3171.22 166,097.21 ± 5908.53 0.189

Bold denotes statistical significance at p < 0.05

p values: obtained by ANCOVA for adjusted mean and standard error

Values were adjusted for age, sex, education, smoking, drinking, obesity, diabetes, hypercholesterolemia, and hypertension by ANCOVA in GLM. Superscript denotes same groups according to Bonferroni’s post hoc multiple comparison test