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. 2021 Aug 9;21:780. doi: 10.1186/s12879-021-06481-1

Table 4.

Logistic regression models predicting in-hospital mortality with continuous and categorical values of CD4 + T cells

Variable Crude OR
(95%CI)**
Univariate p Adjusted OR (95%CI)** Multivariate p Adjusted OR (95%CI)## Multivariate p
Age (1 year increase) 1.06 (1.04–1.09)  < 0.0001 1.04 (1.01–1.09) 0.021 1.04 (1.01–1.09) 0.018
Female gender 2.81 (1.49–5.28) 0.001 3.35 (1.54–7.99) 0.003 3.18 (1.40–7.20) 0.006
CCI* 1.30 (1.15–1.45)  < 0.0001 1.10 (0.91–1.33) 0.321 1.09 (0.90–1.32) 0.373
qSOFA* 5.12 (2.60–10.08)  < 0.0001 3.85 (1.77–8.41) 0.001 4.00 (1.84–8.67)  < 0.001
PCT, ng/mL* 1.01 (1.01–1.02)  < 0.0001 1.01 (1.00–1.02) 0.198 1.01 (1.00–1.02) 0.227
CD4 + T, cells/µL* 0.99 (0.99–1.10)  < 0.0001 0.99 (0.99–1.00) 0.002
CD4 + T, cells < 400/µL 7.75 (3.18–18.93)  < 0.0001 5.3 (1.65–17.00) 0.005
PLT/µL* 0.99 (0.99–1.00) 0.005 1.00 (1.00–1.01) 0.409 1.01 (1.00–1.01) 0.374
Lymphocytes, cells/µL* 0.32 (0.17–0.58)  < 0.0001 0.97 (0.58–1.64) 0.919 0.70 (0.31–1.58) 0.398

CCI Charlson Comorbidity Index, qSOFA quick Sequential Organ Failure Assessment, PCT procalcitonin, PLT platelet, OR odds ratio, IC confidence interval;

*1-unit increase

Parameters of the models: ** Hosmer–Lemeshow goodness of fit p = 1.00; area under the receiving operator curve (ROC) = 0.89;

##Hosmer–Lemeshow goodness of fit p = 0.99; area under the receiving operator curve (ROC) = 0.89