Cyclization of pentameric peptides with different amino acids in the 4th residue from N-terminal.
Peptide number | Cyclic peptide sequence | Linear peptide precursor | Monomer : dimer |
---|---|---|---|
17 | (TTY-Tz4)cy | Fmoc-Pra-TTY-Az4 | 8.02 : 1 |
24 | (TTW-Tz4)cy | Fmoc-Pra-TTW-Az4 | 59.1 : 0 |
25 | (TTF-Tz4)cy | Fmoc-Pra-TTF-Az4 | 6.28 : 1 |
26 | (TTV-Tz4)cy | Fmoc-Pra-TTV-Az4 | 6.34 : 1 |