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| Peptide | Cyclic peptide | Linear peptide precursor | % converteda | Monomer : dimer |
|---|---|---|---|---|
| 1 | (YYTYT-Tz4)cy | Fmoc-Pra-YYTYT-Az4 | 87.4 | 8.28 : 1 |
| 2 | (Tz4-YYTYT)cy | Fmoc-Az4-YYTYT-Pra | 78.8 | 7.02 : 1 |
| 3 | (YYTYT-Tz4)cy-(PEG)5 | Fmoc-Pra-YYTYT-Az4-(PEG)5 | 53.5 | 4.41 : 1 |
Compared to pure linear starting material.
