Cyclization of Gly or Ser containing peptides with seven to ten amino acids.
Peptide | Cyclic peptide | Linear peptide precursor | Monomer : dimer | Number of amino acids |
---|---|---|---|---|
1 | (YYTYT-Tz4)cy | Fmoc-Pra-YYTYT-Az4 | 8.28 : 1 | 7 |
12 | (SYYTYT-Tz4)cy | Fmoc-Pra-SYYTYT-Az4 | 8.98 : 1 | 8 |
13 | (GSYYTYT-Tz4)cy | Fmoc-Pra-GSYYTYT-Az4 | 5.54 : 1 | 9 |