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. 2021 Jan 27;11(8):4842–4852. doi: 10.1039/d0ra07491h

Cyclization of Gly or Ser containing peptides with seven to ten amino acids.

Peptide Cyclic peptide Linear peptide precursor Monomer : dimer Number of amino acids
1 (YYTYT-Tz4)cy Fmoc-Pra-YYTYT-Az4 8.28 : 1 7
12 (SYYTYT-Tz4)cy Fmoc-Pra-SYYTYT-Az4 8.98 : 1 8
13 (GSYYTYT-Tz4)cy Fmoc-Pra-GSYYTYT-Az4 5.54 : 1 9