Table 3.
Overall and sex-race stratified hypertension incidence and adjusted RRs by quartile of CRP, JNC7 hypertension definition
| CRP quartile by group | n Cases/N at risk | Hypertension incidence (95%) CI) | Adjusted RR (95% CI) |
|---|---|---|---|
| All | |||
| Q1 | 713/1629 | 44% (41, 46%) | Ref |
| Q2 | 817/1652 | 49% (47, 52%) | 1.06 (0.99, 1.14) |
| Q3 | 859/1631 | 53% (50, 55%) | 1.10 (1.02, 1.18) |
| Q4 | 954/1636 | 58% (56, 61%) | 1.19 (1.12, 1.28) |
| Males | |||
| White | |||
| Q1 | 261/588 | 44% (41, 49%) | Ref |
| Q2 | 287/586 | 49% (45, 53%) | 1.06 (0.94, 1.19) |
| Q3 | 317/585 | 54% (50, 58%) | 1.13 (1.01, 1.27) |
| Q4 | 325/585 | 56% (52, 60%) | 1.14 (1.02, 1.28) |
| Black | |||
| Q1 | 90/166 | 54% (47, 62%) | Ref |
| Q2 | 101/166 | 61% (54, 69%) | 1.08 (0.90, 1.28) |
| Q3 | 95/167 | 57% (50, 65%) | 1.03 (0.86, 1.24) |
| Q4 | 109/166 | 66% (59, 73%) | 1.16 (0.98, 1.37) |
| Females | |||
| White | |||
| Q1 | 228/624 | 37% (33, 41%) | Ref |
| Q2 | 273/628 | 43% (40, 48%) | 1.07 (0.94, 1.22) |
| Q3 | 308/628 | 49% (45, 53%) | 1.16 (1.02, 1.31) |
| Q4 | 312/628 | 50% (46, 54%) | 1.14 (1.01, 1.30) |
| Black | |||
| Q1 | 145/257 | 56% (51, 63%) | Ref |
| Q2 | 146/258 | 57% (51, 63%) | 0.96 (0.83, 1.11) |
| Q3 | 168/259 | 65% (59, 71%) | 1.12 (0.98, 1.28) |
| Q4 | 178/257 | 69% (64, 75%) | 1.14 (0.99, 1.30) |
Q1–4 indicates each quartile. Adjusted for age, baseline systolic BP, and region. The CI estimated through modified Poisson model. Abbreviations: BP, blood pressure; CI, confidence interval; CRP, C-reactive protein; RR, risk ratios; JNC 7, Joint National Commission 7.