Table 2.
Connections with the Median Raphe
| Placebo Control | z Value | THC Control | z Value |
|---|---|---|---|
| Anterior cingulate cortex | −2.42 | Medial dorsal thalamus | −2.53 |
| Dorsomedial tegmental area | 2.50 | Ventromedial thalamus | −2.46 |
| Raphe linear | 2.73 | Central gray | 2.40 |
| Reticulotegmental nucleus | 2.77 | Interpeduncular nucleus | 2.49 |
| Interpeduncular nucleus | 2.91 | Anterior pretectal nucleus | 2.49 |
| Pontine reticular nucleus oral | 3.21 | Dorsal raphe | 2.71 |
| Periaqueductal gray | 3.73 | Pontine reticular nucleus oral | 2.86 |
| Dorsomedial tegmental area | 3.11 | ||
| Raphe linear | 3.36 | ||
| Placebo Paclitaxel | z Value | THC Paclitaxel | z Value |
| Medial septum | −3.23 | Frontal association cortex | −2.91 |
| Central medial thalamus | −2.54 | Dorsal lateral striatum | −2.46 |
| Entorhinal cortex | 2.35 | 10th Cerebellar lobule | −2.42 |
| Pontine reticular nucleus caudal | 2.41 | Flocculus cerebellum | 2.40 |
| Ventral tegmental area | 2.43 | Anterior lobe pituitary | 2.52 |
| Pedunculopontine tegmentum | 2.45 | Central gray | 2.64 |
| Raphe magnus | 2.49 | Reticulotegmental nucleus | 2.96 |
| Precuniform nucleus | 2.56 | Interpeduncular nucleus | 3.06 |
| Retrosplenial cortex | 2.57 | Pontine reticular nucleus oral | 3.15 |
| Lemniscal nucleus | 2.59 | Dorsomedial tegmentum | 3.32 |
| Anterior pretectal nucleus | 2.62 | Raphe linear | 3.89 |
| Principal sensory nucleus trigeminal | 2.79 | ||
| Inferior colliculus | 2.82 | ||
| Reticulotegmental nucleus | 2.90 | ||
| Central gray | 2.91 | ||
| Visual 2 cortex | 2.91 | ||
| Temporal cortex | 2.93 | ||
| Ectorhinal cortex | 2.95 | ||
| Pontine reticular nucleus oral | 3.01 | ||
| 2nd Cerebellar lobule | 3.05 | ||
| Visual 1 cortex | 3.14 | ||
| 3rd Cerebellar lobule | 3.16 | ||
| Reticular nucleus midbrain | 3.23 | ||
| Superior colliculus | 3.40 | ||
| Raphe linear | 3.46 | ||
| Dorsomedial tegmentum | 3.55 | ||
| Interpeduncular nucleus | 3.62 |
THC, Δ9-tetrahydrocannabinol.