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WT and mutant PHDs used for all-atom membrane simulations with membrane composition of DOPC-DOPS-PIP2 (80:19:1).
| Membrane + PHD variant | Simulation time (ns) |
|---|---|
| Wild type | 500 |
| I533A | 500 |
| F579A | 500 |
| K539A | 500 |
| K583A | 500 |
| Y600L | 500 |
| I533A-F579A | 500 |
| F579K-K583A | 500 |
| F579A-S581K | 500 |
| K539A-K583A | 500 |
