TABLE 2.
PMB resistance of different S. epidermidis mutants
| Strain | Relevant genotype | PMB MIC (μg/ml)a |
|---|---|---|
| NIH051475 | 64 | |
| ALC9220 | ΔgraS | 8 |
| ALC9221 | ΔgraS WTR | 64 |
| ALC9222 | ΔgraS/pEPSA5::vraG | 8b |
| ALC9223 | ΔgraS/pEPSA5::vraFG | 4b |
| ALC9224 | IMMW2 graS | 64 |
| ALC9225 | ΔEL::Ala9 graS | 8 |
| ALC9226 | ΔEL::AYEISVESV graS | 16 |
| ALC9227 | ΔEL::DYDFPIDSL graS | 16 |
| ALC9228 | ΔvraG | 16 |
| ALC9229 | ΔvraG WTR | 64 |
| ALC9230 | ΔEL vraG | 16 |
| ALC9231 | ΔEL vraG WTR | 64 |
| ALC9232 | ΔGL vraG | 16 |
| ALC9233 | ΔGL vraG WTR | 64 |
| ALC9234 | ΔGL::Gly10 vraG | 16 |
| ALC9235 | vraF-G40A | 8 |
| ALC9236 | vraF-G40A WTR | 64 |
a
MICs are representative of a 105 initial inoculum incubated for 48 h at 37°C unless indicated otherwise. All values represent averages of triplicates.
b
The strain MIC is representative of a 105 initial inoculum with 48 h of incubation at 37°C with 1% xylose induction.