Table 4. Molecular docking of GK with Aβ and tau pathology associated GK targets.
Target | PDB | Score (kcal/mol) |
MMP3 | 3OHO | –6.56 |
LCK | 3KMM | –6.5 |
CDK5 | 4AU8 | –6.41 |
NTRK2 | 4AT3 | –6.01 |
GSK3β | 2O5K | –5.86 |
BACE1 | 3QBH | –5.61 |
CFTR | 3GD7 | –5.61 |
Target | PDB | Score (kcal/mol) |
MMP3 | 3OHO | –6.56 |
LCK | 3KMM | –6.5 |
CDK5 | 4AU8 | –6.41 |
NTRK2 | 4AT3 | –6.01 |
GSK3β | 2O5K | –5.86 |
BACE1 | 3QBH | –5.61 |
CFTR | 3GD7 | –5.61 |