Table 3. Crude and adjusted hazards ratios (95% confidence intervals) for incident type 2 diabetes mellitus (T2DM) during the follow-up from March 2008 to December 2012 by baseline RGS-TUG score and stratified by obesity status.
| Number | Incidence of T2DM per 100 person-year | Crude model HR (95% CI) | Adjusted model† HR (95% CI) | |
| Total | ||||
| RGS-TUG score | ||||
| 4 (best) | 583 | 0.08 | 0.00 | 0.00 |
| 3 | 915 | 0.11 | 1.42 (0.82, 2.44) | 1.29 (0.73, 2.29) |
| 2 | 1,124 | 0.13 | 1.68 (1.00, 2.81)* | 1.53 (0.88, 2.66) |
| 1 | 785 | 0.18 | 2.43 (1.45, 4.07)** | 1.78 (0.98, 3.22) |
| 0 (poorest) | 485 | 0.29 | 3.76 (2.24, 6.32)*** | 2.87 (1.52, 5.41)** |
| P for trend | <0.001 | 0.001 | ||
| Normal weight | ||||
| RGS-TUG score | ||||
| 4 (best) | 436 | 0.07 | 0.00 | 0.00 |
| 3 | 645 | 0.07 | 1.07 (0.52, 2.21) | 0.78 (0.36, 1.67) |
| 2 | 739 | 0.09 | 1.38 (0.70, 2.72) | 0.88 (0.42, 1.84) |
| 1 | 448 | 0.15 | 2.39 (1.22, 4.68)* | 0.91 (0.40, 2.08) |
| 0 (poorest) | 204 | 0.15 | 2.37 (1.08, 5.18)* | 0.94 (0.34, 2.56) |
| P for trend | 0.001 | 0.96 | ||
| Overweight/obesity | ||||
| RGS-TUG score | ||||
| 4 (best) | 100 | 0.12 | 0.00 | 0.00 |
| 3 | 221 | 0.26 | 2.14 (0.81, 5.64) | 2.22 (0.82, 6.03) |
| 2 | 335 | 0.23 | 1.95 (0.76, 5.00) | 2.05 (0.76, 5.54) |
| 1 | 318 | 0.24 | 2.06 (0.80, 5.29) | 1.96 (0.70, 5.47) |
| 0 (poorest) | 277 | 0.40 | 3.35 (1.33, 8.44)* | 3.01 (1.04, 8.69)* |
| P for trend | 0.006 | 0.12 | ||
RGS-TUG score: a composite score of relative grip strength (RGS) and timed up and go (TUG) test, with 4 indicating best physical function and 0 indicating poorest physical function.
Incident T2DM: defined by a history of self-reported physician-diagnosed diabetes or glucose-lowering treatment during follow up or fasting glucose ≥7.0 mmol/l or 2hPG ≥11.1 mmol/l and without T2DM at baseline; Normal weight: 18.5 kg/m2 ≤ BMI <25 kg/m2; Overweight/obesity: BMI ≥25 kg/m2.
†adjusting for sex, age, education, occupation, smoking status, alcohol use and self-rated health.
*P < 0.05; **P < 0.01; ***P < 0.001.