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Combination of catalpol promoted the effects of treadmill to reduce PTSD associated depressive and anxiety behaviors. (A, B) Mobility time of different groups in FST and TST. (C) Time of the mice for staying in the center region in OFT. (D) Time of the mice for staying in the open arm during EPM. One-way ANOVA, ***p < 0.001 vs. control; #p < 0.05, ###p < 0.001 vs. PTSD; +p < 0.05, ++p < 0.01 vs. exercise treatment group.
