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. 2021 Jul 29;13(14):18689–18700. doi: 10.18632/aging.203313

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Copyright: © 2021 Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Adult neurogenesis is required for catalpol to promote exercise therapeutic effects to panic memory retrieve and antidepressant. (A) Experimental procedure to block the adult hippocampal neurogenesis with TMZ injection. (B) Daily freezing time response change among different treatments. (C) Statistical analysis of the mobility time in FST among different treatments. (D) Statistical analysis of the staying time at center region in OFT among different treatments. (E) Statistical analysis of the swimming time at target zone in probe trail among different treatments. One-way ANOVA, ^*p < 0.05, ^***p < 0.001, ^****p < 0.0001.